Mapch®K145CosmeticsandToiletriespreservativewithoutN-/O-formalsMicrobicideforbroad-spectrumprotectionagainstbacteria Description:Mapch®K145isaliquidcosmeticpreservative,®K145isnotrmendedforproductsthatareintendedformucousmembranes,orforlipsticksortooth®K145hasabroad,balancedspectrumofeffectagainstbacteria,yeastsandmouldfungi.Itactseveninverylowuse-concentrations. Usedin:Cosmetics,Toiletries,Emulsions,wettissues,shampoos,bathpreparationsandhandcleansingpreparations Advantages:*LiquidpreparationbasedonMethylchloroisothiazolinone,Methylisothiazolinoneand2-Bromo-2-Nitropropane-1,3-Diol,Suitableforpreservationofabroadrangeofwaterbasedproducts*Broad,balancedspectrumofeffectagainstbacteria,yeastsandmouldfungiEffectiveeveninverylowuse-concentrations*EffectiveinpHrangesupto8*FreeofVOCananicsolvents Product-specificproperties:Materiapatibility:Concentrate:InthemateriapatibilitytestswiththeconcentrateofMapch®K145,stainlesssteel,hardpolyvinylchloride(hardPVC),polyethylene(PE),polystyrene(PS)andpolycarbonate(PC)provedtobesuitablematerialorhandlingtheundilutedproduct.Othermetallicmaterialsshouldnotbeused.Alsosoftpolyvinylchloride(softPVC)––provedunsuitable.AssealingmaterialwhenhandlingundilutedMapch®K145,polytetrafluor-ethylene(PTFE)shouldbepreferred.OthersealingmaterialscouldleadtosevereswellingortopronounceddiscolourationofMapch®:ThebehaviourofMapch®K145in0.20%aqueoussolutionwithregardtomateriapatibilitywasnotsignificantlydifferentfromthatofthetapwaterusedforthedilution.NoipatibilitieswithplasticshavebeenobservedwithproductspreservedwithMapch®K145.Effectonsurfacetension:ThesurfacetensionofwaterisslightlyreducedbytheadditionofMapch®K145.Witha0.2%solutioninwateritis70mN/m(water:73mN/m).Foamingbehaviour:InthefoamingtestinaccordancewithDIN53902,a0.10%solutionofMapch®:Inwateraswellasinthepolarsolventssuchas1,2-propyleneglycol,glycerol,triethyleneglycol,Mapch®K145isunlimitedlysoluble.In2-phenoxyethanolMapch®K145islimitedlysoluble.Innon-polarsolventsitisonlylimitedlysoluble,inpurehydrocarbonsitispracticallyinsoluble. Physico-chemicalproperties:Appearance:clear,colourless–yellowishliquidColourindex(Gardner):max.3Odour:characteristicRefractiveindexnD:approx.1.351Density(20℃):approx.1.08g/mlVapourpressure(20℃):approx.25hPaFlashpoint(DIN51758):>100℃Flowtime(DIN53211,20℃):<15DINsecondsViscosity(BrookfieldRVT,20℃):UL-Adapter/.:approx.7mPasWatersolubility(20℃):unlimited Fieldsofapplication:Theoptimumuselevelshouldbeevaluatedbymeansofarepeatedchallengetest(e.g.atMaplechemTechnicalandMicrobiologicaldept).LimitorlabellingcanbeseenfromtheseparateMaplechemlabellingsheet.Usebiocidessafely.Alwaysreadthelabelandproductinformationbeforeuse. Indicationoruse:General:Mapch®K145shouldinprincipleonlybeincorporatedintotheproducttobepreservedinthecoolingphaseatatemperaturelowerthan40℃.Inpractice,addingMapch®K145togetherwiththefragrancehasprovedeffective.HighpHvalues(>8.0)shouldbeavoidedwhenincorporatingMapch®®:Inemulsionswermendnotexceedingauseconcentrationof0.15%Mapch®K145,:Forshampoos,bathpreparationsandhandcleansingpreparationsgoodpreservationresultsareachievedwith0.05–0.30%Mapch®:Inwettissueswermendnotexceedingause-con-centrationof0.15%Mapch®K145,correspondingto7.5ppmisothiazolinones.EuxylK145isnotrmendedforproducts,thatareintendedformucousmembranes.Forotherusespleasecontactus. Chemicapatibility:Ingeneral,itissibleforinteractionstooccurbetweenvariousactiveingredientsandauxiliarysubstancesincos,certainipatibilitiesofMapch®K145withotheringredientshavebeenestablished,:Mapch®K145iullyeffectivebothinanionicaswellascationicandnon-ionicsystems.HighpHvalues(>pH8.0)shouldbeavoided.AcidicpHvalueshavenonegativeinfluenceontheeffectivenesspatibilitywithsurfactantsMapch®K145provedtohavegoopatibilitywithan-ionicsurfactantssuchassulphates,ethersulphatesandsulphosuccinates,aswellaswithnon-ionogenicsurfactants.ThbinationwithDi-andTriethanolamidesshouldbeavoidedduetotheriskofnitrosamineformationpatibilitywithsulphiteions:Mapch®K145isinactivatedbysulphiteions.Excessivesulphite>10ppmmustbeavoided. Microbiologicalefficacy:Mapch®K145isequallyeffectiveagainstbacteria,®K145toperformeffectivelyindestroyinanismsinproductsalreadycontaminated,aminimumcontacttimeof48hoursisnecessary.SincetheeffectofMapch®K145takesplacethroughchemicalreactionswiththemicranisms,whenitisusedinheavilycontaminatedproductslossofactiveingredientmustbetakenintoaccount.Goodproductionhygiene,aswellastheuseofrawmaterialswithlowmicranismlevelsasaresultofcorrectrawmaterialcontrol,areofcoursevitalprerequisiteortheproductionofmicrobiologicallyfaultlesinishedproducts. MICvalues:Determinationoftheminimuminhibitoryconcentrationintheserialdilutiontestproducedthefollowingvalues:Species ATCC-No. MICvalue[PPM]Gram-negative:Burgholderiacepacia 17759 150Enterobactergergoviae 33028 250Escherichiacoli 11229 250Klebsiellapneumoniae 4352 250Pseudomonasaeruginosa 15442 500Pseudomonaluorescens 17397 125Pseudomonasputida 12633 125Gram-itive:Kocuriarhizophila 9341 250Staphylococcusaureus 6538 500Staphylococcusepidermidis 12228 500Mouldfungi:Aspergillusniger 6275 1000Penicilliumfuniculosum 36839 65Yeasts:Candidaalbicans 10231 250 Germcountreductiontest:DilutionsofMapch®K145arepreparedwithsteriletapwater.50mlportionsoftheendsolutionsareeachinoculatedwith0.5mlmicranismsuspension(initialmicranismcountapprox.108cfu/ml):R-phrase(s)R34,R43,R52/53S-phrase(s)S24,S26,S35,S36/37/39,S45LabellingC(Corrosive)Forfurtherhazardinstructionsandsafetyadvicepleaserefertotheactualmaterialsafetydatasheet. Environmentalinformation:Mapch®K145containsonlybiodegradablponents.DilutionsofMapch®K145donotnormallyinterferewiththeoperationofwastewatertreatmentplants.ThecanistersanddrumsusedbyMaplechemaremadeofpolyethylene(HDPE)andarelabelledaccordingly.ThecontainersarecoveredbyareturnschemethatensurescollectionoftheusedcontainerreeofchargeandappropriatereusealloverEurope.ThelabelsaremadeofPE.MaplechempackagingmaterialscontainnoPVCandcanberecycled.Forfurtherinformationpleaseaskforourdetailedenvironmentalreport. Listingsandapprovalsofactiveingredients:EINECS/ELINCS(Europe)TSCA(USA)ECL(Korea)DSL/NDSL(Canada)ENCS(Japan)PICCS(Philippines)AICS(Australia)IECSC(China)BFRXIV,XXXVIFDA175.105/176.170 Transport&Storage:Dangerousgoods:YesUN-Number:1760Packaginggroup:IIIPackagesizes:25kg,200kg,1000kgShelflife:24MonthsStorage:Protectfromfrost,heatanddirectsunlight.Storeatroomtemperatureintheoriginalcontainer. EN/Version01.00/RevisionDate:07.07.2008/Thisproductinformationisnotautomaticallyupdated.
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